Wegovy Side Effects in Week 1: What’s Normal and What’s Not

Wegovy Side Effects in Week 1: What’s Normal and What’s Not

Wegovy side effects in Week 1: What’s normal, what’s not, and how to manage nausea, fatigue, bloating, and more early on.

If you're starting Wegovy and already feeling off, you're not alone. Week 1 is when side effects are most likely to appear.

The good news? Most symptoms are common, short-lived, and manageable. But some can be disruptive or even alarming if you're not expecting them.

Here’s what to watch for in your first week, and how to handle it.

What Dose Am I Starting On?

In New Zealand, most people start Wegovy at 0.25 mg once weekly. This is the lowest dose and is designed to give your body time to adjust.

You won’t see much weight loss in this first stage. It’s more about preparing your system and minimising side effects before increasing the dose in Week 5.

Most Common Week 1 Side Effects

  • Nausea
  • Bloating or early fullness
  • Fatigue or low energy
  • Constipation
  • Burping, reflux, or mild stomach discomfort
  • Headache
  • Loss of appetite

These symptoms typically appear within the first 24–48 hours after your injection and settle within a few days.

What’s Normal (and Manageable)

✅ Feeling mildly queasy after eating
✅ Needing to eat smaller meals than usual
✅ Sleeping more or having low energy
✅ Bloating after meals or a few skipped bowel movements
✅ No interest in certain foods or smaller appetite

These are signs the medication is doing its job, slowing down digestion and resetting your appetite signals.

What’s Not Normal (Time to Speak to a Doctor)

🚫 Vomiting that doesn’t stop
🚫 Severe stomach pain or cramping
🚫 Inability to eat or drink
🚫 Dizziness, confusion, or fainting
🚫 Symptoms that worsen day after day instead of improving

These could be signs of a reaction that needs attention, especially if you’ve had gallbladder issues, diabetes, or GI disorders in the past.

7 Quick Tips to Feel Better in Week 1

  1. Start with simple, bland meals — toast, eggs, soups, and rice are great
  2. Avoid greasy, fried, or heavy foods
  3. Don’t overeat — stop eating when you feel about 70% full
  4. Stay upright after meals — don’t lie down right away
  5. Use peppermint tea or ginger chews for nausea
  6. Sip water steadily all day — don’t chug
  7. Get light movement in — like a 10-minute walk after meals

Most patients feel better within 3–5 days, and often feel more normal by Week 2.

Should I Skip My Next Dose?

No, not unless your doctor advises it. Skipping doses can reset your progress and cause stronger side effects when you restart.

If you’re struggling, talk to your provider. They may recommend:

  • Staying on the current dose longer
  • Adjusting your food strategy
  • Prescribing anti-nausea medication if needed

Final Thought

The first week on Wegovy can be tough, but for most people, it gets easier. If you're feeling off, that's normal. If you're feeling overwhelmed, that’s also normal. The key is not to panic, stay hydrated, eat gently, and reach out if you need help.

With a few adjustments, most people push through Week 1 and go on to see meaningful results.

Start Wegovy With a Supported, Safe Plan

At Well Revolution, we offer a free initial consultation to determine if Wegovy is safe and appropriate for you.

If prescribed, your $80 treatment plan includes:

  • A prescription for 3 months of treatment
  • A custom titration schedule (starting at 0.25 mg)
  • Three months of expert medical care and follow-up
  • Access to your dedicated doctor and care team any time

Wegovy Side Effects in Week 1: What’s Normal and What’s Not

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