How to Inject Mounjaro: Technique, Sites, and Tips

If you've never given yourself an injection before, it can feel intimidating. The good news: Mounjaro uses a simple pen device that makes the process straightforward. Here's what you need to know.

‍

The Mounjaro KwikPen

Mounjaro comes in a pre-filled pen device. You don't need to draw up medication or handle needles separately. The pen does most of the work, you just need to:

1. Attach a new needle
2. Select your dose
3. Insert and press the button
4. Dispose safely

‍

Where to Inject

Approved injection sites include:

• Abdomen: At least 5cm away from your belly button; avoid the area directly around it
• Front of thighs: Middle section of the upper leg
• Back of upper arms: This can be harder to reach yourself; some people get help

‍

Why Site Rotation Matters

Don't inject in the same spot every time. Rotating sites:

• Prevents lumps or hardened areas (lipohypertrophy)
• Reduces skin irritation
• Ensures consistent absorption

A simple rotation: use your left side one week, right side the next. Within each side, vary the exact spot slightly.

‍

Step-by-Step Injection

1. Wash your hands thoroughly
2. Check the medication: It should be clear and colourless; don't use if cloudy or contains particles
3. Attach a new needle to the pen
4. Clean the injection site with an alcohol swab; let it dry
5. Pinch the skin gently (optional, but can help)
6. Insert the needle at a 90-degree angle
7. Press and hold the button until the pen indicates the dose is complete
8. Wait 10 seconds before removing the needle
9. Remove and dispose of the needle in a sharps container

‍

Common Mistakes to Avoid

• Injecting into bruised or irritated skin: Wait for healing first
• Rushing: Hold the button and wait the full time
• Not rotating sites: This causes problems over time
• Reusing needles: Always use a fresh needle
• Injecting cold medication: Let it reach room temperature first (reduces discomfort)

‍

Managing Discomfort

Most people find injections minimally painful, but if you experience discomfort:

• Let the pen warm to room temperature before injecting
• Inject slowly
• Try different sites to find what's most comfortable
• Relax the muscle in the injection area

‍

Timing Your Injection

• Choose the same day each week
• Set a phone reminder
• You can take it any time of day, with or without food
• Some people prefer evenings (to sleep through any initial nausea)

‍

Disposal

Used needles must go in a sharps container, not regular rubbish. You can:

• Get a sharps container from your pharmacy
• Return full containers to pharmacies for safe disposal

‍

Getting Support

If you're nervous about self-injecting, our care team can provide guidance and support. Many people who were initially anxious find it becomes routine quickly.