Wegovy 0.25mg: Why You Might Not Feel Anything (Yet)
Wegovy 0.25mg is a starter dose, not for weight loss yet. Learn why it matters and when to expect real changes to begin.
Wegovy 0.25mg is a starter dose, not for weight loss yet. Learn why it matters and when to expect real changes to begin.
If you’ve just started Wegovy and are on the 0.25 mg dose, you might be wondering why nothing seems to be happening. No weight loss. No reduced appetite. No real change.
That’s normal.
The 0.25 mg dose isn’t designed to cause weight loss just yet, it’s there to help your body ease into treatment. Here’s why that matters, what to expect next, and when things are likely to start working.
The 0.25 mg dose is considered a "starter" dose. It’s not meant to suppress your appetite or cause noticeable weight loss.
Instead, its job is to help your body get used to semaglutide (the active ingredient in Wegovy) and reduce the chance of side effects like nausea, vomiting, or stomach upset.
You’re still getting the benefits of starting the treatment, but in a gentler way that prepares you for the more active doses coming next.
Wegovy is a GLP-1 receptor agonist. It works by:
At 0.25 mg, these effects are just starting. Your system is adjusting, and your gut and brain are beginning to respond, even if you can’t feel it yet.
Think of it like laying a foundation. It may not feel exciting now, but it’s critical for long-term success.
Most people begin noticing changes between the 0.5 mg and 1.0 mg doses, usually around weeks 5 to 8.
Some people report feeling slightly more satisfied after meals or a slight drop in cravings at 0.25 mg, but for many, noticeable effects take time.
Wegovy’s dose schedule is designed for gradual escalation:
Each step is spaced to help you tolerate the medication safely and comfortably.
It’s best to stick to the weekly schedule. Injecting early doesn’t speed things up, it increases your risk of nausea or other side effects.
If you’re tolerating the medication well, that’s a great sign. It means you’re on track to increase the dose safely, and your care team will check in before your next step up.
Even if you’re not feeling big changes yet, this is a great time to:
Late afternoon or evening cravings are common and often the first thing to improve once your dose increases.
Don’t worry if nothing dramatic is happening yet. You’re not doing anything wrong, and the medication is working as intended.
The 0.25 mg dose is about preparing your body, not rapid results. What you’re doing now sets the stage for safe, effective progress in the weeks ahead.
If you have questions or want help along the way, we’re here. Message us anytime.
At Well Revolution, we offer a free initial consultation to determine if Wegovy is safe and appropriate for you.
If prescribed, your $80 treatment plan includes:
Concerned, need advice, a prescription, refill or referral?
Chat with a GP now